| The College Board | 501(c)(3) | New York, NY | $942 million |
| Cooperative for Assistance and Relief Everywhere (CARE) | 501(c)(3) | Atlanta, GA | $614 million |
| Step Up For Students | 501(c)(3) | Jacksonville, FL | $533 million |
| American Jewish Joint Distribution Committee (JDC) | 501(c)(3) | New York, NY | $292 million |
| Combined Jewish Philanthropies (CJP) | 501(c)(3) | Boston, MA | $280 million |
| International Baccalaureate (IB) | 501(c)(3) | Bethesda, MD | $195 million |
| Scholarship America | 501(c)(3) | St Peter, MN | $175 million |
| Harlem Childrens Zone (HCZ) | 501(c)(3) | New York, NY | $120 million |
| Year Up | 501(c)(3) | Boston, MA | $105 million |
| Veterans of Foreign Wars of the United States (VFW) | 501(c)(19) | Kansas City, MO | $91 million |
| New York Road Runners (NYRR) | 501(c)(3) | New York, NY | $87 million |
| United Negro College Fundation (UNCF) | 501(c)(3) | Washington, DC | $79 million |
| California Academy of Sciences | 501(c)(3) | San Francisco, CA | $76 million |
| 92nd Street Y (92Y) | 501(c)(3) | New York, NY | $75 million |
| The American Legion | 501(c)(19) | Indianapolis, IN | $71 million |
| United States Fund for Unicef in Kind Assistance Corporation (UNICEF) | 501(c)(3) | New York, NY | $65 million |
| US Committee for Refugees and Immigrants (USCRI) | 501(c)(3) | Arlington, VA | $59 million |
| Catholic Charities of the Archdiocese of New York | 501(c)(3) | New York, NY | $55 million |
| Sports and Arts in Schools Foundation (SASF) | 501(c)(3) | Woodside, NY | $40 million |
| Harvard Club of New York City (HCNY) | 501(c)(7) | New York, NY | $35 million |
| Jewish Federation of Greater Philadelphia (JFGP) | 501(c)(3) | Philadelphia, PA | $29 million |
| Military Officers Association of America (MOAA) | 501(c)(19) | Alexandria, VA | $25 million |
| Girls Incorporated | 501(c)(3) | New York, NY | $24 million |
| Reading Partners | 501(c)(3) | Oakland, CA | $24 million |
| Alliance for a Healthier Generation | 501(c)(3) | Portland, OR | $22 million |
| Catholic Health Association of the United States (CHA) | 501(c)(3) | Saint Louis, MO | $22 million |
| Salvation Army World Service Office (SAWSO) | 501(c)(3) | Alexandria, VA | $21 million |
| Teach for All | 501(c)(3) | New York, NY | $20 million |
| Summer Search | 501(c)(3) | San Francisco, CA | $19 million |
| College Possible | 501(c)(3) | Saint Paul, MN | $19 million |
| First Place for Youth | 501(c)(3) | Oakland, CA | $19 million |
| Samuel Field Y | 501(c)(3) | Little Neck, NY | $18 million |
| Network for Teaching Entrepreneurship (NFTE) | 501(c)(3) | New York, NY | $18 million |
| Common Application | 501(c)(3) | Arlington, VA | $18 million |
| Girl Scout Council of the Nation's Capital (GSCNC) | 501(c)(3) | Washington, DC | $16 million |
| Cradles To Crayons | 501(c)(3) | Brighton, MA | $16 million |
| Salesforce Com Foundation | 501(c)(3) | San Francisco, CA | $15 million |
| Homeboy Industries | 501(c)(3) | Los Angeles, CA | $14 million |
| Future Business Leaders of America Phi Beta Lambda Inc -- Group Return (FBLA-PBL) | 501(c)(3) | Reston, VA | $13 million |
| Lesbian and Gay Community Services Center Inc (LGBT) | 501(c)(3) | New York, NY | $13 million |
| Council for Christian Colleges and Universities (CCCU) | 501(c)(3) | Washington, DC | $12 million |
| Tragedy Assistance Program for Survivors (TAPS) | 501(c)(3) | Arlington, VA | $11 million |
| Association of Governing Boards of Universities and Colleges (AGB) | 501(c)(3) | Washington, DC | $11 million |
| Community Partners in Action (CPA) | 501(c)(3) | Hartford, CT | $10 million |
| After-School All-Stars (ASAS) | 501(c)(3) | Los Angeles, CA | $9.6 million |
| Distributive Education Clubs of America (DECA) | 501(c)(3) | Reston, VA | $9.1 million |
| Pencils of Promise (PoP) | 501(c)(3) | New York, NY | $8.6 million |
| GOOD+ Foundation | 501(c)(3) | New York, NY | $7.8 million |
| Marine Corps Association (MCA) | 501(c)(19) | Quantico, VA | $7.6 million |
| National Guard Association of the United States (NGAUS) | 501(c)(19) | Washington, DC | $6.8 million |
| Camfed | 501(c)(3) | San Francisco, CA | $6.7 million |
| Out & Equal | 501(c)(3) | San Francisco, CA | $6.2 million |
| Girl Scouts of Greater New York (GSGNY) | 501(c)(3) | New York, NY | $6.0 million |
| College Summit | 501(c)(3) | Washington, DC | $4.3 million |
| Transgender Law Center (TLC) | 501(c)(3) | Oakland, CA | $3.0 million |
| International Studies Association (ISA) | 501(c)(3) | Storrs, CT | $3.0 million |
| Breakthrough New York | 501(c)(3) | New York, NY | $2.2 million |
| Worldwide Orphans (WWO) | 501(c)(3) | Maplewood, NJ | $2.2 million |
| GiGi's Playhouse | 501(c)(3) | Hoffman Est, IL | $1.8 million |
| Southern New Hampshire University Student Government Association | 501(c)(3) | Manchester, NH | $1.1 million |
| Fulbright Association | 501(c)(3) | Gainesville, FL | $899,367 |
| Bike to the Beach | 501(c)(3) | Washington, DC | $831,795 |
| International Mountain Bicycling Association (IMBA) | 501(c)(3) | Boulder, CO | $372,338 |
| Catholic Charities of the Diocese of Arlington (CCDA) | 501(c)(3) | Arlington, VA | - |
| Girl Scouts of the United States of America (GSUSA) | 501(c)(3) | New York, NY | $145 million |
| In-Q-Tel (IQT) | 501(c)(3) | Arlington, VA | $139 million |
| International Fellowship of Christians and Jews (IFCJ) | 501(c)(3) | Chicago, IL | $131 million |
| Oklahoma State University Foundation | 501(c)(3) | Stillwater, OK | $110 million |
| University of Washington Foundation | 501(c)(3) | Seattle, WA | $82 million |
| American Near East Refugee Aid (ANERA) | 501(c)(3) | Washington, DC | $67 million |
| Georgia State University Foundation | 501(c)(3) | Atlanta, GA | $64 million |
| Semper Fi Fund | 501(c)(3) | CMP Pendleton, CA | $36 million |
| Rady Children's Hospital Foundation | 501(c)(3) | San Diego, CA | $33 million |
| Greater Lawrence Community Action Council (GLCAC) | 501(c)(3) | Lawrence, MA | $30 million |
| Wayfinder Family Services | 501(c)(3) | View Park, CA | $28 million |
| Catholic Charities of Southern Nevada | 501(c)(3) | Las Vegas, NV | $25 million |
| Scus Head Start Programs | 501(c)(3) | Fairfield, CT | $24 million |
| Best Buddies International | 501(c)(3) | Miami, FL | $24 million |
| Girl Scouts of Northern California | 501(c)(3) | Alameda, CA | $20 million |
| Boys & Girls Clubs of San Francisco (BGCSF) | 501(c)(3) | San Francisco, CA | $14 million |
| Serious Fun Children's Network | 501(c)(3) | Westport, CT | $14 million |
| Latin American Youth Center (LAYC) | 501(c)(3) | Washington, DC | $14 million |
| Easter Seals Serving DC MD VA | 501(c)(3) | Silver Spring, MD | $14 million |
| Delta Sigma Theta Sorority | 501(c)(7) | Washington, DC | $13 million |
| United States Naval Academy Alumni Association | 501(c)(3) | Annapolis, MD | $12 million |
| Rochester School for the Deaf (RSD) | 501(c)(3) | Rochester, NY | $11 million |
| Coptic Orphans (CO) | 501(c)(3) | Merrifield, VA | $10 million |
| The Bridge Family Center Incorporated | 501(c)(3) | W Hartford, CT | $7.5 million |
| Florence Crittenton Services of Arizona | 501(c)(3) | Phoenix, AZ | $6.8 million |
| Reading Is Fundamental (RIF) | 501(c)(3) | Washington, DC | $6.3 million |
| Girls Incorporated of Alameda County | 501(c)(3) | Oakland, CA | $6.1 million |
| Minnesota State University Moorhead Alumni Foundation (MSUMAF) | 501(c)(3) | Moorhead, MN | $6.0 million |
| Point Foundation | 501(c)(3) | Los Angeles, CA | $5.1 million |
| American Humanist Association (AHA) | 501(c)(3) | Washington, DC | $2.4 million |
| Back-To-School Clothing Drive Association | 501(c)(3) | Phoenix, AZ | $815,548 |
| World Vision | 501(c)(3) | Federal Way, WA | $1.0 billion |
| Institute of International Education (IIE) | 501(c)(3) | New York, NY | $592 million |
| Teach for America (TFA) | 501(c)(3) | New York, NY | $272 million |
| Boy Scouts of America (BSA) | 501(c)(3) | Irving, TX | $228 million |
| Wounded Warrior Project (WWP) | 501(c)(3) | Jacksonville, FL | $226 million |
| Orange County Community Foundation (OCCF) | 501(c)(3) | Newport Beach, CA | $73 million |
| The Associated: Jewish Community Federation of Baltimore | 501(c)(3) | Baltimore, MD | $51 million |
| West Point Association of Graduates (WPAOG) | 501(c)(3) | West Point, NY | $48 million |
| University of North Dakota Alumni Association | 501(c)(3) | Grand Forks, ND | $41 million |
| Catholic Charities of the Archdiocese of Washington (CCAW) | 501(c)(3) | Washington, DC | $37 million |
| Jewish Federation of Greater Washington (JFGW) | 501(c)(3) | North Bethesda, MD | $36 million |
| North Dakota State University Foundation and Alumni Association | 501(c)(3) | Fargo, ND | $25 million |
| American Association of University Women (AAUW) | 501(c)(3) | Mclean, VA | $25 million |
| Navy-Marine Corps Relief Society (NMCRS) | 501(c)(3) | Arlington, VA | $23 million |
| Boys' Latin School of Maryland | 501(c)(3) | Baltimore, MD | $20 million |
| Jewish Federation of Metropolitan Chicago | 501(c)(3) | Chicago, IL | $110 million |
| National Merit Scholarship Corporation (NMSC) | 501(c)(3) | Evanston, IL | $53 million |
| Education Service Center Region 13 | 501(c)(3) | Austin, TX | $48 million |
| Hispanic Scholarship Fund (HSF) | 501(c)(3) | Gardena, CA | $47 million |
| Communication Service for the Deaf (CSD) | 501(c)(3) | Austin, TX | $29 million |
| Jewish Federation of Greater Metrowest NJ | 501(c)(3) | Whippany, NJ | $28 million |
| After School Matters | 501(c)(3) | Chicago, IL | $25 million |
| Highland Dallas Foundation | 501(c)(3) | Dallas, TX | $19 million |
| Higher Learning Commission (HLC) | 501(c)(3) | Chicago, IL | $16 million |
| Boston Educational Development Foundation (BEDF) | 501(c)(3) | Roxbury, MA | $10 million |
| Military Officers Association of America Scholarship Fund (MOAA) | 501(c)(3) | Alexandria, VA | $6.4 million |
| Goodwill Industries of South Florida | 501(c)(3) | Miami, FL | $140 million |
| Jewish Federation of Cleveland | 501(c)(3) | Cleveland, OH | $93 million |
| Global Alliance for TB Drug Development (TB Alliance) | 501(c)(3) | New York, NY | $61 million |
| Lions Clubs International Foundation (LCIF) | 501(c)(3) | Oak Brook, IL | $55 million |
| Moose International | 501(c)(8) | Mooseheart, IL | $49 million |
| Brain & Behavior Research Foundation | 501(c)(3) | New York, NY | $31 million |
| Jewish Federation of Palm Beach County Inc | 501(c)(3) | West Palm BCH, FL | $25 million |
| Girl Scouts of Eastern Pennsylvania (GSEP) | 501(c)(3) | Miquon, PA | $19 million |
| Society of St. Vincent de Paul Archdiocesan Council of St. Louis | 501(c)(3) | St Louis, MO | $19 million |
| Great Lakes Higher Education Corporation | 501(c)(3) | Madison, WI | $16 million |
| Mutual Beneficial Association (MBA) | 501(c)(8) | Berwyn, PA | $16 million |
| Girl Scouts of Greater Atlanta | 501(c)(3) | Mableton, GA | $16 million |
| Soledad Enrichment Action (SEA) | 501(c)(3) | Los Angeles, CA | $16 million |
| The Jewish Agency for Israel | 501(c)(3) | New York, NY | $15 million |
| Girl Scouts of Orange County | 501(c)(3) | Irvine, CA | $14 million |
| Mandel Jewish Community Center of Cleveland | 501(c)(3) | Beachwood, OH | $13 million |
| Jewish Federation of Greater Indianapolis (JFGI) | 501(c)(3) | Indianapolis, IN | $12 million |
| Jewish Community Center of Greater Washington (JCCGW) | 501(c)(3) | Rockville, MD | $12 million |
| Girl Scouts of Northeast Texas (GSNETX) | 501(c)(3) | Dallas, TX | $12 million |
| Girl Scouts San Diego | 501(c)(3) | San Diego, CA | $11 million |
| American Nuclear Society (ANS) | 501(c)(3) | La Grange PK, IL | $10 million |
| Urban League of Broward County | 501(c)(3) | FT Lauderdale, FL | $9.9 million |
| Girl Scouts of Central Indiana | 501(c)(3) | Indianapolis, IN | $9.4 million |
| Tekeyan Cultural Association (TCA) | 501(c)(3) | Watertown, MA | $8.8 million |
| Girl Scouts of Central and Southern New Jersey | 501(c)(3) | Cherry Hill, NJ | $8.6 million |
| California University of Pennsylvania (Cal U) | 501(c)(3) | California, PA | $7.7 million |
| Camp Fire First Texas | 501(c)(3) | Fort Worth, TX | $5.7 million |
| Discovery Learning Alliance (DLA) | 501(c)(3) | Silver Spring, MD | $5.2 million |
| Girl Scouts of the Jersey Shore | 501(c)(3) | Farmingdale, NJ | $5.0 million |