1. Directory of nonprofits
  2. Locations
  3. Missouri
  4. St. Louis

St. Louis area nonprofits

There are 24,203 organizations in the greater St. Louis metro area, including the cities of St. Louis and St. Charles. Combined, these St. Louis metro nonprofits employ 471,730 people, earn more than $81 billion in revenue each year, and have assets of $172 billion.
Skip to:

Job trends for St. Louis nonprofits

Employees per organizationNumber of organizations
0
 
5,205
1-10
 
1,306
11-25
 
429
26-100
 
375
101 to 1,000
 
294
1,000+
 
59
Key takeaways for employment stats:

Sizes of nonprofits in St. Louis

Revenues per organizationNumber of organizations
< $250k
 
6,264
$250k to $1M
 
1,655
$1M to $5M
 
908
$5M to $25M
 
400
$25M to $100M
 
146
$100M+
 
102
Key takeaways for revenue stats:

Types of nonprofits in St. Louis

Nonprofit typeNumberRevenues
Foundations
 
3,990
 
$2,590,696,214
Religious organizations
 
3,757
 
$288,266,730
Educational institutions
 
3,322
 
$9,474,902,710
Human service organizations
 
1,779
 
$2,215,761,887
Recreation, sports, and social clubs
 
1,514
 
$474,866,460
Business and community development organizations
 
1,318
 
$714,499,197
Arts, culture, and humanities nonprofits
 
1,247
 
$456,448,971
Mutual assistance organizations
 
920
 
$1,872,740,272
Health organizations
 
750
 
$58,521,861,876
Public sector, public co-ops, and veteran organizations
 
745
 
$1,228,001,310
Showing 10 of 25 categories

Directory of nonprofits in St. Louis

Want to add filters to this list, or drill down on results in detail? Open in the Cause IQ search interface
1-20 of 24,203

Pedal the Cause

To provide critical funding for cancer research at Siteman Cancer Center and Siteman Kids at St. Louis Children's Hospital through our annual cycling challenge.
Revenue
$7.3m
Assets
$2.8m
Employees
12
EIN
27-2233336
IRS type
501(c)(3)

Catholic Health Association of the United States

Cha's mission is to advance the Catholic Health ministry of the United States in caring for people and communities.
Revenue
$37.0m
Assets
$76.3m
Employees
84
EIN
43-0653271
IRS type
501(c)(3)

American Association of Orthodontists

American Association of Orthodontists connects patients with qualified orthodontists, represents 19,000 specialists, and advances orthodontic care through education, research, advocacy, and public awareness.
Revenue
$25.0m
Assets
$35.0m
Employees
42
EIN
43-0763598
IRS type
501(c)(6)

St. Louis Area Food Bank (SLAFB)

St. Louis Area Food Bank's mission is to feed hungry people by distributing food throughout the bi-state region and engage our community in the fight against hunger.
Revenue
$95.9m
Assets
$57.3m
Employees
121
EIN
43-1253102
IRS type
501(c)(3)

Places for People Incorporated (PfP)

Places for People Incorporated provides recovery-based, evidence-informed mental health and substance use care, coordinating housing and supports to improve community well-being.
Revenue
$36.6m
Assets
$29.5m
Employees
485
EIN
23-7433924
IRS type
501(c)(3)

Saint Louis Art Museum Foundation

The St. Louis Art Museum Foundation, a Missouri nonprofit corporation, was established in 1985 for the sole benefit of, and to carry out the purposes of, the mission and activities of the Saint Louis Art Museum.
Revenue
$29.7m
Assets
$319.2m
Employees
0
EIN
43-1374479
IRS type
501(c)(3)

Missouri Botanical Garden Board of TRUSTEES

Missouri Botanical Garden Board of TRUSTEES leads plant research, education, and conservation, advancing biodiversity protection and sharing knowledge that preserves and enriches life.
Revenue
$61.0m
Assets
$414.1m
Employees
547
EIN
43-0666759
IRS type
501(c)(3)

Ascension St Agnes Foundation

To serve as an instrument to assist, advance, and strengthen St. Agnes Healthcare by developing philanthropic resources, sponsoring healthcare services, supporting education in medical fields, and supporting humanitarian endeavors.
Revenue
$9.0m
Assets
$30.6m
Employees
0
EIN
52-1415083
IRS type
501(c)(3)

Humane Society of Missouri

Humane Society of Missouri is a nonprofit organization that provides adoption services for formerly-owned or abandoned pets. It has an animal cruelty taskforce that provides comprehensive investigative and emergency rescue services for animals statewide.
Revenue
$31.6m
Assets
$150.6m
Employees
246
EIN
43-0652638
IRS type
501(c)(3)

Children's Cancer Assistance Fund (NCCS)

The National Children's Cancer Society (NCCS) provides emotional, financial and educational support to children with cancer, their families and survivors.
Revenue
$8.3m
Assets
$6.8m
Employees
19
EIN
37-1227890
IRS type
501(c)(3)

Community Health Commission of Missouri

The Community Health Commission of Missouri operates to achieve zero Health disparities through Community and Health system partnerships.
Revenue
$1.7m
Assets
$8.8m
Employees
16
EIN
43-1883638
IRS type
501(c)(3)

Ascension St Vincent Cardiac Services

To own free standing outpatient and diagnostic cardiac catherization laboratories and support other entities that provide cardiac services to the community and to support and encourage the activities and purposes of Ascension Health and St.Vincent Health.
Revenue
$128.2m
Assets
$795.9m
Employees
509
EIN
35-1869951
IRS type
501(c)(3)

Anderson Hospital

Anderson has been making a difference in the healthcare of Madison County residents since 1977. They are an independent, not for profit hospital dedicated to creating a health care setting.
Revenue
$229.2m
Assets
$258.5m
Employees
1,518
EIN
37-0662561
IRS type
501(c)(3)

Sacred Heart Foundation

Sacred Heart Foundation is the private fund raising arm of the Sacred Heart Health System, soliciting support from the philanthropic community to support all facets of health care within the Sacred Heart system.
Revenue
$6.2m
Assets
$26.8m
Employees
7
EIN
59-2436597
IRS type
501(c)(3)

Ascension Seton

Ascension Seton: Leading provider of healthcare in Central Texas with Level I trauma facilities, free-standing children's hospital, and spiritual-centered care.
Revenue
$3.3b
Assets
$3.4b
Employees
16.7k
EIN
74-1109643
IRS type
501(c)(3)

Horizon Housing Foundation (HHF)

Horizon Housing Foundation provides safe, affordable housing for families and seniors and supports them through programs that promote economic self-sufficiency and improve their quality of life.
Revenue
$230.6m
Assets
$917.8m
Employees
5
EIN
74-2979359
IRS type
501(c)(3)

TW LD Mceachearn

TW LD Mceachearn is a private foundation that made three grants last year. The trustee is Wells Fargo Bank N A. The grantees include Mceachern Endowment Fund. It is located in Las Vegas, NV.
Revenue
$12.4m
Assets
$136.0m
Employees
1
EIN
58-6255314
IRS type
501(c)(3)

Columbia St Mary's

Columbia St Mary's is a Catholic health ministry that operates three hospitals focusing on spiritually-centered and holistic care.
Revenue
$183.1m
Assets
$229.7m
Employees
4,768
EIN
39-1834639
IRS type
501(c)(3)

BioGenerator

BioGenerator builds and invests in a thriving biosciences sector, providing commercialization guidance and feedback on business strategies.
Revenue
$8.7m
Assets
$14.0m
Employees
0
EIN
83-0349805
IRS type
501(c)(3)

Penta Group

To develop the residents' skills to their highest functioning level, to promote, safeguard, and protect the human dignity, constitutional rights, and individual liberties of residents.
Revenue
$27.2m
Assets
$25.2m
Employees
399
EIN
37-1224606
IRS type
501(c)(3)
Want more insights on nonprofits in St. Louis?
There's a whole lot more to Cause IQ than what you see here. Additional filters, personnel information, peer benchmarking, Salesforce integration, vendor lists, etc. Access all the information your company needs in one place, already collected.
Schedule a demo
Over 200 customers use Cause IQ to grow, maintain, and serve their nonprofit clients.
Methodology: Cause IQ mines all tax-exempt organizations that file a Form 990, Form 990-EZ, or Form 990-PF with the IRS. We collect and aggregate this information from OCR'd paper taxreturns, XML e-file taxreturns, IRS-provided extract, the Business Master File, and Cause IQ secret sauce for data cleaning, categorization, classification, analytics, etc.
Cause IQ is a website that helps companies grow, maintain, and serve their nonprofit clients, and helps nonprofits find additional foundation funding. Our data and tools help professionals prospect for nonprofits, research opportunities, benchmark their clients, and enrich existing information.
Nonprofits
Product
Customers
About

© 2026 Nonprofit Metrics LLC
Terms of Service and Privacy Policy